Diabetic nephropathy is characterized by increased glomerular permeability to proteins and excessive extracellular matrix accumulation in the mesangium, eventually resulting in glomerulosclerosis and progressive renal impairment ().Recently, increasing attention has been paid to the role of podocytes in the pathogenesis of proteinuric conditions (2,3).
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Objective. To evaluate the prevalence of prolonged QT interval and dispersion in a population-based cohort of type 2 diabetic patients and their relationship with clinical and metabolic variables. Design. Cross-sectional population-based cohort. Setting. Diabetes clinics and general ...
Oct 17, 2012· Positive fluid balance has been associated with an increased risk for mortality in critically ill patients with acute kidney injury with or without renal replacement therapy (RRT). Data on fluid accumulation prior to RRT initiation and mortality are limited. We aimed to study the association between fluid accumulation at RRT initiation and 90-day mortality.
Liver transplantation (LT) has revolutionized the treatment of patients with advanced liver disease. However, access to this lifesaving procedure is limited because demand for …
Type 1 and type 2 diabetes are generally accepted to be associated with increased bone fracture risk. However, the pathophysiological mechanisms of diabetic bone disease are poorly understood, and whether the associated increased skeletal fragility is a comorbidity or a …
1. Introduction. Skin is a barrier that protects the body against external mechanical, physical, chemical and biological factors. From the histological point of view, it is a highly multilayer composite consisting of three main structures: epidermis, dermis, and hypodermis.
RS, PC, FH-L, MS, SH, SO, SB, GU, JL, MP, JM, KS, YT, PA, KN, RO, JD, and PH contributed data and assisted writing the manuscript. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Limitations of Albuminuria. Albuminuria is a marker for kidney/glomerular disease as well as for CVD risk and is often the first clinical indicator of the presence of DKD ().It is a clinically useful tool for predicting prognosis and for monitoring response to therapy.
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Mogensen CE, Neldam S, Tikkanen I, Oren S, Viskoper R, Watts RW, Cooper ME (2000) Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and …
The skin, easily accessible for medical examination, is affected in many ways by liver transplantation. Mucocutaneous manifestations of advanced liver disease and dermatologic conditions associated with specific hepatic diagnoses generally improve after liver transplantation.
Pharmacological inhibition of PSD-95 is a promising therapeutic strategy in the treatment of stroke, and positive effects of monomeric and dimeric PSD-95 inhibitors have been reported in numerous studies.
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Xenoestrogen makes the uterine walls thinner and fragile. [34] When comparing fish from above a wastewater treatment plant and below a wastewater treatment plant, studies found disrupted ovarian and testicular histopathology, gonadal intersex, reduced gonad size, vitellogenin induction, and …
Non-receptor tyrosine kinases (nRTKs) are cytosolic enzymes that are responsible for catalysing the transfer of a phosphate group from a nucleoside triphosphate donor, …
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Summary. Laparoscopic surgery has become popular in recent years, but few studies have addressed analgesia for this type of surgery. We conducted a prospective double-blind randomised trial on 36 cases of laparoscopic colorectal surgery to determine the influence of …
Main Results. An algorithm-based guideline for screening and treatment of the complications of diabetes was developed. The emphasis is on prevention of atherosclerotic disease, and prevention, screening, and early treatment of microvascular disease.
Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives Victoria L Fisher,1 Abd A Tahrani2–4 1School of Medicine, University of Nottingham, Nottingham, 2Institute of Metabolism and Systems Research, University of Birmingham, 3Department of Diabetes and Endocrinology, Birmingham Heartlands Hospital, 4Centre for Endocrinology, Diabetes and …
Simonton CA, Chatterjee K, Cody RJ, Kubo SH, Leonard D, Daly P, Rutman H. Milrinone in congestive heart failure: acute and chronic hemodynamic and clinical evaluation. J Am Coll Cardiol .
Rapid sequence induction and intubation is a standard and accepted method in the administration of general anaesthesia in patients with aspiration risk. Thus, the goal is first to ensure a secure airway and then to administer general anaesthesia ( 2 ).
Listed below are all abstracts that have been accepted for the Eighteenth Symposium. These include oral presentations, posters, and software demonstrations.
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Background. Smoking is associated with increased macrovascular and microvascular complications in people with diabetes. In addition to other concomitant vascular perturbations, it also seems to influence the cardiometabolic parameters, which may partly explain the accelerated rate of vascular complications in smokers with diabetes.
